Medicine’s preemptive strike

Imagine getting a message from your doctor, not because something is wrong, but because something might become wrong, and there’s still time to prevent it. That is the idea behind

AI PRO, and the C-Pi platform (CLALIT PROACTIVE & PREVENTATIVE INTERVENSION), a new artificial intelligence system launched by Clalit Health Services, Israel’s largest healthcare provider. Designed to help doctors spot medical risks earlier and tailor care more precisely, the system is already changing the way family medicine works, often long before patients feel unwell. Instead of waiting for a complaint or a worrying symptom, Clalit physicians can now reach out to patients proactively, all based on a detailed picture of each patient’s personal health history, and aligned with the most up-to-date clinical guidelines.

Modern medicine generates an overwhelming amount of data – test results, diagnoses, prescriptions, and clinical guidelines that are constantly changing. AI PRO was built to help doctors make sense of it all. Every night, the system scans millions of medical records, cross-checking individual patient data against the most recent, cutting-edge clinical. It then highlights patients who may be at higher risk and offers physicians clear, evidence-based recommendations. The final decision always remains with the doctor. “AI PRO doesn’t replace medical judgment – it supports it,” said Prof. Doron Netzer, head of medicine in Clalit’s community division. “This isn’t a chatbot or a gimmick. It’s a tool that helps doctors see patterns and risks they might otherwise miss, and act earlier to protect their patients’ health.”

The system is already active in areas such as diabetes, dyslipidemia, hypertension, obesity, osteoporosis, viral hepatitis, medication monitoring, ect.. Soon, it will expand into mental health, helping clinicians identify and address conditions such as depression and anxiety before they worsen.

Each month, family physicians approve about 100,000 recommendations generated by AI PRO. When a doctor adopts one, the patient receives a message via text or the Clalit app notifying what’s recommended. It’s a major shift in mindset: from reactive medicine to care that anticipates problems rather than chases them.

One of the most ambitious plans for the coming year is integrating genetic data into the system, something not yet done at this scale anywhere in the world. In practice, that could mean fewer side effects and less trial and error. A patient who needs medication to lower cholesterol, for example, could receive a recommendation not only based on general guidelines but also on how their body is genetically likely to respond. “This is about meeting patients where they are – biologically, not just statistically,” explained Prof. Ran Balicer, Clalit’s deputy Director General and Chief innovation Officer. “We’re moving away from a system that waits for people to feel sick, toward one that helps keep them healthy in the first place.”

For all its technological sophistication, Clalit emphasizes that AI PRO operates behind the scenes. Every recommendation is reviewed and approved by a physician, and patients can always speak directly with their doctor. “Technology only works in healthcare if people trust it,” said Avi Atia,

Deputy CEO, CIO & Head of IT and Digital Division at Clalit. “That’s why transparency and human oversight are built into every step.” The system runs on highly secure infrastructure and meets strict privacy and regulatory standards, an essential requirement for handling sensitive medical information.

With nearly five million members, Clalit’s scale has turned AI PRO into a real-world laboratory for the future of medicine. International consulting firm Deloitte has already cited the system as a model for how large healthcare organizations can shift from reactive treatment to preventive, predictive care – strengthening community medicine, easing hospital workloads, and improving outcomes for millions of patients. For patients, though, the impact may feel much simpler: a message from a doctor at just the right moment, before a problem becomes a crisis.