Beersheba District Court president Benny Sagi died in a car crash on Highway 6, a police spokesperson confirmed on Sunday evening.
A vehicle came from an open area, striking Sagi, who was riding his motorcycle, critically injuring him.
Magen David Adom paramedics attended the scene, stating that he showed no signs of life, and were forced to pronounce him dead.
Israel Police officers are investigating the circumstances that led to the incident.
Israeli politicians and members of the judiciary reacted to the news of Sagi's death.
"I learned with shock and great sorrow the news of the untimely death of Sagi," Justice Minister Yariv Levin wrote.
He was "a brilliant jurist, an exceptional judge - beloved and respected by lawyers and litigants alike," he added.
"I came to know Sagi when I interned at the Central District Attorney's Office about 20 years ago when he was a prosecutor," Knesset Speaker Amir Ohana said.
"He was a straight and honest man, highly knowledgeable in criminal law, with a rare ability to find paths of compromise and agreement," he recalled.
"He was head and shoulders above others, but even as president of a district court, his heart did not grow haughty, and the modesty and humility so characteristic of him accompanied him even in this lofty position. He also had a sense of humor that is quite rare in this profession," Ohana continued.
Herzog: 'A brilliant, sharp-minded jurist'
"Sagi was a brilliant and sharp-minded jurist, a tremendous judge who combined immense professional knowledge with exceptional integrity," President Isaac Herzog commented.
"I was constantly impressed from afar by the rare blend he embodied - a judge of stature and authority, with a moving personal story, who was known as a man of values, humble and kind-hearted, who always saw the person standing before him and strove for peace and mediation," he added.
"Sagi was a talented and promising judge - a leader, beloved and admired by all who knew him, who achieved professional accomplishments at a young age, and his death is a great loss to the judicial system in which he served," a Judicial Authority spokesperson said.
"Sagi was a man who stood head and shoulders above others. Proof of the uniqueness and depth of the loss is the fact that in such a turbulent and polarized period, he was a consensus of excellence both as a judge and as a manager in the court system," Israel Bar Association head Amit Becher wrote.
"He was a people person, and I saw him as a role model and inspiration, and a perfect candidate to fill the most senior roles in the judicial system. His tragic passing is a loss for the IBA and for me personally," he concluded.
"Sagi was a central and respected figure in the judicial system, a jurist of stature and a public servant who acted with dedication, professionalism, and deep public responsibility," the Justice Ministry said.